mebendazole CAS NO.31431-39-7

Toluene of thiazole is a broad-spectrum deworming drugs, are completely kill hook worm eggs and whipworm eggs as well as part of the role of the kill hatched from eggs, beta tubulin of insect body strong and force, in very low concentrations can, by influencing the insect body sugar metabolism and related energy generated inhibiting the microtubule polymerization, cause the disappearance of the insect body skin or intestinal cells, optional and irreversible inhibition of insect body from intestinal uptake of glucose and other nutritional ingredients, finally led to the deaths of insect body. Apply to treat human and animal body for whipworm, pinworm, hookworm, tapeworm, dung round worms and worm infections caused by a single or multiple worm, but the echinococcosis is invalid.

Toluene of azole melt the coupling agent is also a kind of oxidation of phosphoric acid, fumaric acid reductase inhibits mitochondria, reduce glucose transport, which affect the production of ATP.

Toluene of azole mixed suspension can inhibit intestinal parasites of glucose uptake, lead to worm storage of glycogen depletion in the body, reduce insect body adenosine triphosphate formation, but does not affect blood glucose levels in the host. Ultrastructure observation, toluene of azole mixed suspension cells and intestinal cells can cause worm capsule microtubules in cytoplasm degeneration, gore matrix endocrine particles accumulate, transportation congestion, cytoplasm dissolved, fully absorb cells degeneration, thus caused death worm.