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Andarine CAS NO.401900-40-1
- FOB Price: USD: 10,000.00-10,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T
- Available Specifications:
pharmaceutical grade(1-1000)Kilogrampharmaceutical grade(1-1000)Kilogram
- Product Details
Keywords
- SARM S4
- Wuhan ZeShanCheng Biomedical Technology Co., Ltd.
- CAS:401900-40-1
Quick Details
- ProName: Andarine
- CasNo: 401900-40-1
- Molecular Formula: C19H18F3N3O6
- Appearance: white power
- Application: Pharma;Industry;Agricultural;chemical ...
- DeliveryTime: Delivery within 3or5 days after paymen...
- PackAge: Packaging according to customer needs
- Port: China Main Port
- ProductionCapacity: 10 Kilogram/Week
- Purity: 99%
- Storage: Keep it in dry,shady and cool place
- Transportation: SEA OR AIR
- LimitNum: 1 Kilogram
- Related Substances: no
- Residue on Ignition: 0.2%
- Heavy Metal: 1ppm
- Valid Period: 2year
- Molecular formula: c19h18f3n3o6
Superiority
SARM S4
English Name: andarine
CAS No.: 401900-40-1
Molecular formula: c19h18f3n3o6
Molecular weight: 441.36
Melting point: 70-74 ℃
Boiling point: 698.7 ± 55.0 ° C (predicted)
Density: 1.47
Storage conditions: refrigerator
Acidity coefficient (PKA) 12.13 ± 0.29 (predicted)
Bioactive andarine is a selective non steroidal androgen receptor (AR) agonist with KI of 4 nm. It has tissue selectivity for anabolic organs
Details
Wuhan ZeShanCheng Biomedical Technology Co., Ltd. is located in Wuhan, the economic and geographical center of China and known as the "thoroughfare of nine provinces". It is a technology-based enterprise integrating R & D and sales. The company adheres to the concept of "technology first, customer first". We always provide customers with good products, technical support and perfect after-sales service.
Main products: cosmetic raw materials (whitening series, preservatives, sunscreens, rheological modifiers, surfactants, etc.), chemical raw materials (catalysts, additives, starting materials, etc.).
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Bioactivity Andarine is a selective non-steroidal androgenreceptor(AR) agonist with a Ki of 4nM and tissue selectivity for anabolic organs. In vitro studies Andarine binds with androgen receptors with a high affinity and Ki of 4nM in vitro. Moreover,10nMAndarine stimulated 93% of androgen receptor-regulated transcription. In vivo studies In vivo,Andarine has a potent anabolic activity and stimulates prostate, seminal vesicle, and levator ANI growth with an ED50 of 0.43mg/day,0.55mg/day, and 0.14mg/day, respectively, in a dose-dependent manner. In addition, the effect of Andarine on FSH did not affect some physiological changes induced by castration, and the dose of 0.5mg or higher per day partially inhibited LH production. After intravenous administration of Andarine at 0.1,1,3, and 10mg/kg, total scavenging power (CL) decreased from 7.4mL/min/kg to 3.1mL/min/kg, steady-state distribution volume (Vss) was 1.39L/kg, and half-life was 229 minutes. In addition, the oral bioavailability of Andarine at doses of 10mg/kg,1mg/kg and 0.1mg/kg was 38%,62% and 91%, respectively. Andarine showed tissue selective pharmacological activity and significantly reduced prostate weight to 79.4% in well-treated rats at 0.5mg/day. Characteristics Andarine is a non-steroidal androgen receptor (AR) selective stimulant.